Fig. 1 · Structure
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Estrone sulfate potassium
Endogenous Estrogen
Estrone sulfate potassium is an inactive form of endogenous estrogen, serving as a substrate for the OATP1B3 transporter. It can be enzymatically converted to Estrone and Estradiol, facilitating their biological activities. This compound effectively stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and promotes the colony formation of dispersed nitrosomethylurea mammary cells, with conversion occurring both in vivo and in vitro. Estrone sulfate potassium is a valuable reagent for research in breast cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 1240-04-6 |
| Applications | Endogenous Estrogen |
| Formula | C18H21KO5S |
| Molecular Weight | 388.52 |
| SMILES | C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OS(=O)([O-])=O)=C4)[C@@]3([H])CC1)C2=O.[K+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.