Fig. 1 · Structure
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Estrone sulfate
Endogenous Estrogen
Estrone sulfate is an endogenous estrogen precursor that can be enzymatically converted into active forms, Estrone and Estradiol. As a substrate of the OATP1B3 transporter, it plays a role in cellular uptake processes. Estrone sulfate has been shown to promote the proliferation of nitrosomethylurea-induced mammary tumors in ovariectomized rat models and enhances colony formation in cultured nitrosomethylurea mammary cells. This compound is particularly relevant for research in breast cancer and estrogen signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 481-97-0 |
| Applications | Endogenous Estrogen |
| Formula | C18H22O5S |
| Molecular Weight | 350.43 |
| SMILES | C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OS(=O)(O)=O)=C4)[C@@]3([H])CC1)C2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.