Fig. 1 · Structure
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Estrone sulfate sodium
Endogenous Estrogen
Estrone sulfate sodium is an inactive endogenous estrogen and a substrate of the OATP1B3 transporter. It can be metabolized into bioactive forms, Estrone and Estradiol, particularly in normal mammary parenchymal cells. This compound has been shown to stimulate the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and enhances colony formation of dispersed nitrosomethylurea mammary cells both in vivo and in vitro. Estrone sulfate sodium serves as a valuable tool for research in breast cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 438-67-5 |
| Applications | Endogenous Estrogen |
| Formula | C18H21NaO5S |
| Molecular Weight | 372.41 |
| SMILES | C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OS(=O)(O[Na])=O)=C4)[C@@]3([H])CC1)C2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.