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Exherin (ADH-1)

Catalog No.: A13689

N-cadherin antagonist

Exherin (ADH-1)

Exherin (ADH-1) Chemical Structure

CAS NO. 229971-81-7

Exherin is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$160.00
25 mg
$280.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • CM Madl, .et al. Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels, Adv Sci, 2019, 1801716
  • Christopher M. Madl, .et al. Maintenance of Neural Progenitor Cell Stemness in 3D Hydrogels Requires Matrix Remodeling, Nat Mater, 2017, Dec; 16(12): 1233-1242 PMID: 29115291
  • Andrew J. Lindsay, .et al. Rab coupling protein mediated endosomal recycling of N-cadherin influences cell motility, Oncotarget, 2017, Dec 1; 8(62): 104717-104732 PMID: 29285208

Biological Activity

Exherin is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.52 mL 87.61 mL 175.23 mL
0.5 mM 3.5 mL 17.52 mL 35.05 mL
1 mM 1.75 mL 8.76 mL 17.52 mL
5 mM 0.35 mL 1.75 mL 3.5 mL

*The above data is based on the productmolecular weight 570.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13689
Actions Antagonist
CAS No. 229971-81-7
Formula C22H34N8O6S2
M. Wt 570.68
Purity >98%
Synonyms NSC729477, ADH-1
SMILES C[[email protected]]1C(=O)N[[email protected]](C(=O)N[[email protected]@H](CSSC[[email protected]@H](C(=O)N[[email protected]](C(=O)N1)CC2=CN=CN2)NC(=O)C)C(=O)N)C(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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