Fig. 1 · Structure

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FabH-IN-2

Antimicrobial Agent

FabH-IN-2 is a novel antimicrobial agent that targets the β-ketoacyl-acyl carrier protein synthase (FabH) enzyme, critical for fatty acid biosynthesis in bacteria. It demonstrates significant antibacterial activity with a minimum inhibitory concentration (MIC) ranging from 1.25 to 3.13 μg/mL against various bacterial strains. Furthermore, FabH-IN-2 exhibits an IC50 of 2.0 μM against FabH derived from Escherichia coli, making it a valuable tool for research in microbiology and the development of new antibacterial therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3040281-87-3
Applications Antimicrobial Agent
Formula C20H18N2O5
Molecular Weight 366.37
SMILES
O=C(NC1=CC(NC=C2C(OC)=O)=C2C=C1)C3=CC(OCCCO4)=C4C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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