Fig. 1 · Structure
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Fabimycin
FabI Inhibitor
Fabimycin is an inhibitor of FabI, targeting the essential enoyl-ACP reductase enzyme involved in the biosynthesis of fatty acids in bacteria. It demonstrates strong antibacterial activity specifically against gram-negative bacteria, including those exhibiting resistance to conventional drugs. This compound is valuable for research into new therapeutic strategies for combating drug-resistant gram-negative infections in vivo.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2651965-71-6 |
| Applications | FabI Inhibitor |
| Formula | C23H25ClN4O3 |
| Molecular Weight | 440.92 |
| SMILES | O=C(/C=C/C(C=C1CC[C@@H]2[NH3+])=CN=C1NC2=O)N(C)CC(O3)=C(C)C4=C3C=CC=C4.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.