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FG-2101

LpxC Inhibitor

FG-2101 is a potent and selective non-hydroxamate inhibitor of LpxC, exhibiting an IC50 of approximately 1 nM. This compound demonstrates exceptional selectivity over both bacterial and human metalloenzymes, making it a valuable tool for research. FG-2101 is applicable in studies of Gram-negative bacterial infections, including those involving drug-resistant strains, facilitating investigations into potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2919723-66-1
Applications	LpxC Inhibitor
Formula	C₃₀H₃₂N₅O₆P
Molecular Weight	589.58
SMILES	N#CC1CN(C1)C[C@H](C2=CC=C(C=C2)C#CC3=CC=C(C=C3)CN4CCOCC4)CC5=C(C(NC=N5)=O)OP(O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.