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Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the ??Thumb 2?? pocket of NS5B.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.86 mL | 99.28 mL | 198.55 mL |
| 0.5 mM | 3.97 mL | 19.86 mL | 39.71 mL |
| 1 mM | 1.99 mL | 9.93 mL | 19.86 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
*The above data is based on the productmolecular weight 503.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21392 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 877130-28-4 |
| Formula | C29H37N5O3 |
| M. Wt | 503.64 |
| Solubility | DMSO |
| Purity | >98% |
| SMILES | O=C(O1)C(CC2=NN(C(C)=C3)C(N=C3C)=N2)=C(O)C[[email protected]@]1(C4CCCC4)CCC5=CC(CC)=NC(CC)=C5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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