Filibuvir

Catalog No.: A21392

non-nucleoside inhibitor

Filibuvir

Filibuvir Chemical Structure

CAS NO. 877130-28-4

Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the ??Thumb 2?? pocket of NS5B.

Availability: In stock

Package Price Qty
1 mg
$72.00
5 mg
$216.00
10 mg
$368.00
50 mg
$1,104.00
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Biological Activity

Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the ??Thumb 2?? pocket of NS5B.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.86 mL 99.28 mL 198.55 mL
0.5 mM 3.97 mL 19.86 mL 39.71 mL
1 mM 1.99 mL 9.93 mL 19.86 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21392
Actions Inhibitor
CAS No. 877130-28-4
Formula C29H37N5O3
M. Wt 503.64
Purity >98%
SMILES O=C(O1)C(CC2=NN(C(C)=C3)C(N=C3C)=N2)=C(O)C[[email protected]@]1(C4CCCC4)CCC5=CC(CC)=NC(CC)=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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