Filipin III is a pentaene macrolide antifungal antibiotic featuring a 28-membered ring, primarily derived from various Streptomyces species including S. filipinensis, S. avermitilis, and S. miharaensis. This compound targets membrane sterols, leading to significant alterations in membrane structure, which disrupts fungal cell integrity. Filipin III is widely utilized in research to study fungal infections and to explore mechanisms of antifungal resistance.
Filipin III is a pentaene macrolide antifungal antibiotic featuring a 28-membered ring, primarily derived from various Streptomyces species including S. filipinensis, S. avermitilis, and S. miharaensis. This compound targets membrane sterols, leading to significant alterations in membrane structure, which disrupts fungal cell integrity. Filipin III is widely utilized in research to study fungal infections and to explore mechanisms of antifungal resistance.
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