Fingolimod

Catalog No.: A17798

S1P antagonist

Fingolimod

Fingolimod Chemical Structure

CAS NO. 162359-55-9

Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.

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5 mg

Regular Price: $50.00

Special Price $40.00

10 mg

Regular Price: $80.00

Special Price $64.00

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Biological Activity

Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.
In vitro DMSO 12 mg/mL (39.03 mM)
Water Insoluble
Ethanol 5 mg/mL (16.26 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.52 mL 162.61 mL 325.22 mL
0.5 mM 6.5 mL 32.52 mL 65.04 mL
1 mM 3.25 mL 16.26 mL 32.52 mL
5 mM 0.65 mL 3.25 mL 6.5 mL

*The above data is based on the productmolecular weight 307.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17798
Actions Antagonist
CAS No. 162359-55-9
Formula C19H33NO2
M. Wt 307.48
Purity >98%
Synonyms Fingolimod; FTY720 (free base)
SMILES OCC(CCC1=CC=C(CCCCCCCC)C=C1)(N)CO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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