Fipamezole is a potent antagonist of the α2-adrenergic receptor, exhibiting Ki values of 9.2 nM, 17 nM, and 55 nM for the human α2A, α2B, and α2C receptors, respectively. This compound serves as an effective anti-dyskinetic agent, making it valuable for research applications in the study of Parkinson's disease and related movement disorders. Its oral bioavailability enhances its utility in various experimental settings.
Fipamezole is a potent antagonist of the α2-adrenergic receptor, exhibiting Ki values of 9.2 nM, 17 nM, and 55 nM for the human α2A, α2B, and α2C receptors, respectively. This compound serves as an effective anti-dyskinetic agent, making it valuable for research applications in the study of Parkinson's disease and related movement disorders. Its oral bioavailability enhances its utility in various experimental settings.
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