Fleephilone is a fungal metabolite derived from Trichoderma harzianum that acts as an HIV REV/RRE binding inhibitor. It effectively disrupts the interaction between the REV protein and RRE RNA, exhibiting an IC50 value of 7.6 μM. This compound is valuable for research focused on HIV replication mechanisms and the development of antiviral strategies targeting RNA-protein interactions.
Fleephilone is a fungal metabolite derived from Trichoderma harzianum that acts as an HIV REV/RRE binding inhibitor. It effectively disrupts the interaction between the REV protein and RRE RNA, exhibiting an IC50 value of 7.6 μM. This compound is valuable for research focused on HIV replication mechanisms and the development of antiviral strategies targeting RNA-protein interactions.
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