Fmoc-Val-Cit-PAB-MMAF-OtBu

Catalog No.: A41479
MMAF-ADC Linker
Fmoc-Val-Cit-PAB-MMAF-OtBu is a linker compound designed for the conjugation of MMAF (monomethyl auristatin F) to antibodies, facilitating the formation of antibody-drug conjugates (ADCs). This versatile linker allows for the selective delivery of the cytotoxic agent to tumor cells, enhancing anti-tumor efficacy while minimizing systemic toxicity. Fmoc-Val-Cit-PAB-MMAF-OtBu is suitable for research applications in ADC development and cancer therapeutics.
Grouped product items
Size Price Stock Qty
5mg
$265.00
In stock
10mg
$435.00
In stock
25mg
$820.00
In stock
50mg
$1,280.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-Val-Cit-PAB-MMAF-OtBu is a linker compound designed for the conjugation of MMAF (monomethyl auristatin F) to antibodies, facilitating the formation of antibody-drug conjugates (ADCs). This versatile linker allows for the selective delivery of the cytotoxic agent to tumor cells, enhancing anti-tumor efficacy while minimizing systemic toxicity. Fmoc-Val-Cit-PAB-MMAF-OtBu is suitable for research applications in ADC development and cancer therapeutics.
Product Information
Catalog NumA41479
FormulaC77H110N10O15
Molecular Weight1415.78
CAS Number863971-54-4
SMILESC(OC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H](CC3=CC=CC=C3)C(OC(C)(C)C)=O)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)[C@H](C)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)[C@H](C)C)=O)C4C=5C(C=6C4=CC=CC6)=CC=CC5
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