Selection Antibiotics & Contamination Control

Selection antibiotics and contamination-control reagents isolate modified cells and keep cultures free of microbes. Stable mammalian cell lines are selected with an antibiotic matched to the resistance gene, such as puromycin, G418, blasticidin S, hygromycin B or phleomycin D1. Ampicillin, carbenicillin, kanamycin and chloramphenicol select bacteria that carry resistance plasmids. Penicillin G with streptomycin, gentamicin, amphotericin B and nystatin are added to media to limit bacterial and fungal contamination. Ciprofloxacin is also used in protocols that remove mycoplasma from infected cultures.

Items 1-25 of 35

  • Amphotericin B
    Cat. No.
    A10073

    Amphotericin B

    Synonyms: Fungilin; Fungizone; AmBisome; Fungisome; Amphocil; Amphotec

    Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. Amphotericin B induces K+ leakage, which is separate from its lethal action, as was demonstrated in human erythrocytes and is due to the inhibitory effect on the Na+/K+ pump.

    50 mg
    $25.00
    100 mg
    $35.00
    All 5 sizes
  • Blasticidin S HCl
    Cat. No.
    A14212

    Blasticidin S HCl

    Synonyms: Blasticidine S HCl

    Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor.

    1 mg
    $25.00
    5 mg
    $70.00
    All 7 sizes
  • Ampicillin Trihydrate
    Cat. No.
    A16408

    Ampicillin Trihydrate

    Synonyms: NCI-C56086

    Ampicillin Trihydrate is a beta-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.

    500 mg
    $25.00
    1 g
    $45.00
    All 2 sizes
  • Ciprofloxacin hydrochloride hydrate
    Cat. No.
    A17555

    Ciprofloxacin hydrochloride hydrate

    Synonyms: Ciprofloxacin Hydrochloride

    Ciprofloxacin Hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline, interfering with the bacterial DNA gyrase, inhibiting the DNA synthesis, and preventing bacterial cell growth.

    500 mg
    $35.00
    1 g
    $55.00
    All 3 sizes
  • Gentamycin sulfate
    Cat. No.
    A10427

    Gentamycin sulfate

    Synonyms: Gentamicins; Gentamycinum; Cidomycin; Gentacycol

    Gentamycin(Gentacycol) is an aminoglycoside antibiotic and was isolated from Micromonospora species

    250 mg
    $30.00
    500 mg
    $45.00
    All 4 sizes
  • Nystatin
    Cat. No.
    A10664

    Nystatin

    Nystatin is a polyene antifungal antibiotic effective against yeast and mycoplasma.

    200 mg
    $20.00
    500 mg
    $35.00
    All 2 sizes
  • Ampicillin sodium
    Cat. No.
    A11810

    Ampicillin sodium

    Synonyms: D-(-)-α-Aminobenzylpenicillin sodium salt

    Ampicillin sodium is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent for microbiological research. Ampicillin sodium is commonly used in cell culture and for selecting genetically modified organisms, as well as in the study of bacterial resistance mechanisms. Its ability to inhibit bacterial growth supports investigations into antibiotic efficacy and microbial interactions.

    500 mg
    $25.00
    1 g
    $30.00
    All 7 sizes
  • Ciprofloxacin
    Cat. No.
    A11838

    Ciprofloxacin

    Synonyms: Bay-09867

    Ciprofloxacin is a potent topoisomerase IV inhibitor that demonstrates significant antibacterial activity as a fluoroquinolone antibiotic. It induces both mitochondrial and nuclear DNA damage, leading to mitochondrial dysfunction and increased reactive oxygen species (ROS) production. Ciprofloxacin exhibits anti-proliferative properties and triggers apoptotic pathways, making it a valuable tool for research applications focused on bacterial infections, oxidative stress, and cancer biology.

    500 mg
    $30.00
    1 g
    $45.00
    All 3 sizes
  • Carbenicillin disodium
    Cat. No.
    A11841

    Carbenicillin disodium

    Synonyms: Sodium carbenicillin

    Carbenicillin disodium is a broad-spectrum semi-synthetic penicillin antibiotic targeting gram-negative bacteria. It exerts its antibacterial activity by inhibiting cell wall synthesis, making it effective in various microbiological applications. Due to its low toxicity, it is also suitable for use in plant tissue research.

    200 mg
    $25.00
    250 mg
    $30.00
    All 7 sizes
  • Hygromycin B
    Cat. No.
    A13796

    Hygromycin B

    Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It acts by inhibiting protein synthesis by inducing the misreading of the m-RNA template in the prokaryote, with the potency to inhibit translation.

    100 mg
    $30.00
    200 mg
    $40.00
    All 6 sizes
  • Kanamycin
    Cat. No.
    A13837

    Kanamycin

    Synonyms: Kanamycin A

    Kanamycin is an orally active antibacterial agent that targets both gram-negative and gram-positive bacteria by inhibiting translocation and causing misreading of mRNA. This aminoglycoside antibiotic demonstrates significant efficacy against Mycobacterium tuberculosis, including both sensitive and drug-resistant strains, as well as Klebsiella pneumoniae. Kanamycin is widely utilized in research applications focused on tuberculosis and pneumonia, providing valuable insights into bacterial infections and treatment strategies.

    100 mg
    $25.00
    200 mg
    $30.00
    All 4 sizes
  • Tetracycline hydrochloride
    Cat. No.
    A14909

    Tetracycline hydrochloride

    Tetracycline hydrochloride is a broad-spectrum antibiotic targeting bacterial protein synthesis. It demonstrates antibacterial activity against a wide array of microorganisms, including gram-positive and gram-negative bacteria, as well as chlamydiae, mycoplasmas, and rickettsiae. This reagent is suitable for research applications involving bacterial infections and studies related to antibiotic resistance mechanisms.

    500 mg
    $30.00
    1 g
    $45.00
    All 6 sizes
  • Enrofloxacin
    Cat. No.
    A16525

    Enrofloxacin

    Synonyms: BAY Vp 2674; PD160788

    Enrofloxacin is a potent bacterial inhibitor belonging to the fluoroquinolone class. It exhibits an MIC90 value of 0.312 μg/mL against Mycoplasma bovis, demonstrating its effectiveness in combating bacterial infections. This compound is widely utilized in research applications focused on antibiotic resistance, microbiology, and the study of bacterial pathogens.

    500 mg
    $35.00
    5 g
    $45.00
    All 3 sizes
  • Penicillin G sodium salt
    Cat. No.
    A16660

    Penicillin G sodium salt

    Synonyms: Benzylpenicillin sodium salt

    Penicillin G sodium salt is a β-lactam antibiotic that inhibits bacterial cell wall synthesis by targeting penicillin-binding proteins. It demonstrates broad-spectrum antibacterial activity against various Gram-positive and some Gram-negative organisms. This reagent is commonly used in microbiological studies to evaluate susceptibility patterns and in the development of antibiotic resistance models.

    100 mg
    $40.00
    200 mg
    $55.00
    All 4 sizes
  • Streptomycin sulfate
    Cat. No.
    A16721

    Streptomycin sulfate

    Streptomycin sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits potent antibacterial activity against a range of Gram-negative and some Gram-positive bacteria, making it useful in both clinical and research settings. This reagent is commonly employed in studies involving microbial resistance, antibiotic efficacy, and protein synthesis mechanisms.

    500 mg
    $35.00
    10 g
    $50.00
    All 3 sizes
  • Ciprofloxacin HCl
    Cat. No.
    A16969

    Ciprofloxacin HCl

    Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline, an fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent

    500 mg
    $25.00
    1 g
    $40.00
    All 3 sizes
  • Benzylpenicillin potassium
    Cat. No.
    A17554

    Benzylpenicillin potassium

    Synonyms: Penicillin G potassium

    Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas

    5 g
    $25.00
    10 g
    $30.00
    All 2 sizes
  • Tetracycline
    Cat. No.
    A18246

    Tetracycline

    Synonyms: Tetracyclinum; Tetracyclin; Deschlorobiomycin

    Tetracycline is a broad-spectrum antibiotic that targets bacterial protein synthesis by binding to the 30S ribosomal subunit, inhibiting translation. It demonstrates activity against a diverse array of microorganisms, including gram-positive and gram-negative bacteria, as well as chlamydiae, mycoplasmas, and rickettsiae. This compound is widely utilized in research related to bacterial infections and antibiotic resistance mechanisms.

    200 mg
    $20.00
    1 g
    $25.00
    All 7 sizes
  • G-418 disulfate
    Cat. No.
    A21002

    G-418 disulfate

    Synonyms: Geneticin sulfate; Antibiotic G-418 sulfate; G418

    G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

    500 mg
    $50.00
    1 g
    $85.00
    All 3 sizes
  • Blasticidin S
    Cat. No.
    A21608

    Blasticidin S

    Blasticidin S is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. Blasticidin S is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells.

    5 mg
    $77.00
    10 mg
    $132.00
    All 4 sizes
  • Enrofloxacin monohydrochloride
    Cat. No.
    A24261

    Enrofloxacin monohydrochloride

    Synonyms: BAY Vp 2674 monohydrochloride; PD160788 monohydrochloride

    Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is a broad-spectrum antibiotic with demonstrated efficacy against *Mycoplasma bovis*, exhibiting a MIC₉₀ of 0.312 μg/mL. In addition to its antibacterial properties, it also shows inhibitory activity against vaccinia virus (VV), indicating potential antiviral applications.

    500 mg
    $45.00
    All 1 sizes
  • Gentamicin
    Cat. No.
    A24633

    Gentamicin

    Synonyms: Septigen; Refobacin; Oksitselanim; Lyramycin; Centicin

    Gentamicin, a potent aminoglycoside antibiotic, functions as a DNase I inhibitor with an IC50 of 0.57 mM. This compound effectively inhibits the growth of various gram-positive and gram-negative bacteria, as well as several strains of mycoplasma in tissue culture. It is widely used in microbiological research and applications involving nucleic acid stability.

    5 mg
    $25.00
    10 mg
    $40.00
    All 6 sizes

Items 1-25 of 35

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