Galanin-B2

Catalog No.: A91019
Peptide
Galanin-B2 is a neuropeptide that targets galanin receptors, demonstrating significant activity in epilepsy models. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for studies related to neurological disorders and potential therapeutic applications in epilepsy research. Its unique properties facilitate investigations into the modulation of neuronal excitability and synaptic transmission.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGalanin-B2 is a neuropeptide that targets galanin receptors, demonstrating significant activity in epilepsy models. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for studies related to neurological disorders and potential therapeutic applications in epilepsy research. Its unique properties facilitate investigations into the modulation of neuronal excitability and synaptic transmission.
Product Information
Catalog NumA91019
FormulaC104H174N24O22
Molecular Weight2112.64
CAS Number944087-28-9
Sequence{Sar}-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Lys-Lys-{Lys(Pal)}-Lys-NH2
Sequence shortening{Sar}-WTLNSAGYLLGPKK-{Lys(Pal)}-K-NH2
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(NCC(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CCCCNC(CCCCCCCCCCCCCCC)=O)=O)CCCCN)=O)CCCCN)=O)CCC2)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)C)=O)CO)=O)CC(N)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)NC(CNC)=O)C=3C=4C(NC3)=CC=CC4
SynonymsNAX-5055
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