Gamma-Glutamyl Transferase-IN-1

Catalog No.: A27853
Gamma-Glutamyl Transferase Inhibitor
Gamma-Glutamyl Transferase-IN-1 is a potent inhibitor of gamma-glutamyl transferase, specifically designed to disrupt its enzymatic function. This β-carboline 1-hydrazide compound exhibits significant antifungal and antibacterial activities by promoting the accumulation of reactive oxygen species, leading to cell membrane disruption and alterations in histone acetylation. It serves as a valuable tool for research investigating the roles of gamma-glutamyl transferase in various biological processes and disease states.
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Size Stock
5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGamma-Glutamyl Transferase-IN-1 is a potent inhibitor of gamma-glutamyl transferase, specifically designed to disrupt its enzymatic function. This β-carboline 1-hydrazide compound exhibits significant antifungal and antibacterial activities by promoting the accumulation of reactive oxygen species, leading to cell membrane disruption and alterations in histone acetylation. It serves as a valuable tool for research investigating the roles of gamma-glutamyl transferase in various biological processes and disease states.
Product Information
Catalog NumA27853
FormulaC19H14FN5O2
Molecular Weight363.35
CAS Number2956809-71-3
SMILESO=C(NNC1=CC=C(F)C=C1)C2=NC(C(N)=O)=CC3=C2NC4=CC=CC=C43
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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