Fig. 1 · Structure
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Ganciclovir sodium
Antiviral Agent
Ganciclovir sodium is a nucleoside analogue that serves as an antiviral agent primarily targeting cytomegalovirus (CMV) and exhibits inhibitory effects against other herpesviruses, including HSV-1, HSV-2, and various adenovirus serotypes. This compound effectively inhibits the in vitro replication of these viruses, showcasing a significant biological activity with an IC50 of 5.2 μM against feline herpesvirus type-1 (FHV-1). Additionally, Ganciclovir sodium's ability to penetrate the brain makes it a valuable tool for studying viral infections and therapeutic interventions in neurovirology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 107910-75-8 |
| Applications | Antiviral Agent |
| Formula | C9H12N5NaO4 |
| Molecular Weight | 277.21 |
| Synonyms | BW 759 sodium; 2'-Nor-2'-deoxyguanosine sodium |
| SMILES | OCC(OCN1C=NC2=C1N=C(N)N=C2O[Na])CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.