GCA-186 is a potent anti-HIV-1 compound that targets the virus's replication machinery. It demonstrates significant antiviral activity against both wild-type and mutated strains of HIV-1, exhibiting EC50 values of 1 nM for IIIB, 180 nM for IIIB-R(Y181C), 1 nM for NL4-3, and 40 nM for NL4-3K103N. This compound is a valuable tool for research on HIV-1 resistance and therapeutic development.
GCA-186 is a potent anti-HIV-1 compound that targets the virus's replication machinery. It demonstrates significant antiviral activity against both wild-type and mutated strains of HIV-1, exhibiting EC50 values of 1 nM for IIIB, 180 nM for IIIB-R(Y181C), 1 nM for NL4-3, and 40 nM for NL4-3K103N. This compound is a valuable tool for research on HIV-1 resistance and therapeutic development.
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