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Biological Activity
GDC-0834 Racemate is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), investigated as a potential treatment for rheumatoid arthritis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.76 mL | 83.79 mL | 167.58 mL |
| 0.5 mM | 3.35 mL | 16.76 mL | 33.52 mL |
| 1 mM | 1.68 mL | 8.38 mL | 16.76 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.35 mL |
*The above data is based on the productmolecular weight 596.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12706 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1133432-46-8 |
| Formula | C33H36N6O3S |
| M. Wt | 596.74 |
| Purity | >98% |
| Synonyms | GDC0834, GDC 0834 |
| SMILES | CC1=C(C=CC=C1NC(=O)C2=CC3=C(S2)CCCC3)C4=CN(C(=O)C(=N4)NC5=CC=C(C=C5)C6C(=O)N(CCN6C)C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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