GDC-0834

Catalog No.: A12706

BTK inhibitor

GDC-0834

GDC-0834 Chemical Structure

CAS NO. 1133432-46-8

GDC-0834 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), investigated as a potential treatment for rheumatoid arthritis.

Availability: In stock

Package Price Qty
5 mg
$180.00
10 mg
$268.00
25 mg
$500.00
50 mg
$726.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GDC-0834 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), investigated as a potential treatment for rheumatoid arthritis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.76 mL 83.79 mL 167.58 mL
0.5 mM 3.35 mL 16.76 mL 33.52 mL
1 mM 1.68 mL 8.38 mL 16.76 mL
5 mM 0.34 mL 1.68 mL 3.35 mL

*The above data is based on the productmolecular weight 596.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12706
Actions Inhibitor
M. Wt 596.74
Formula C33H36N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1133432-46-8
Synonyms GDC0834, GDC 0834
SMILES CC1=C(C=CC=C1NC(=O)C2=CC3=C(S2)CCCC3)C4=CN(C(=O)C(=N4)NC5=CC=C(C=C5)C6C(=O)N(CCN6C)C)C

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