GLP-26

Catalog No.: A18914

HBV capsid assembly modulator

GLP-26

GLP-26 Chemical Structure

CAS NO. 2133017-36-2

GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools.

Availability: In stock

Package Price Qty
1 mg
$80.00
5 mg
$250.00
10 mg
$340.00
50 mg
$900.00
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Biological Activity

GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.78 mL 133.92 mL 267.85 mL
0.5 mM 5.36 mL 26.78 mL 53.57 mL
1 mM 2.68 mL 13.39 mL 26.78 mL
5 mM 0.54 mL 2.68 mL 5.36 mL

*The above data is based on the productmolecular weight 373.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18914
Actions Modulator
M. Wt 373.35
Formula C19H17F2N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2133017-36-2
Synonyms GLP26, GLP 26
SMILES O=C(C1=C(C)C(C(C(NCC#C)=O)=O)=C(C)N1C)NC2=CC=C(F)C(F)=C2

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