GNE-207

Catalog No.: A18844

CBP bromodomain inhibitor

GNE-207

GNE-207 Chemical Structure

CAS NO. 2158266-58-9

GNE-207 is a novel, potent, and orally bioavailable inhibitor of the bromodomain of CBP. GNE-207 has excellent CBP potency (CBP IC50?=?1?nM, MYC EC50?=?18?nM), and it exhibits a good pharmacokinetic profile.

Availability: In stock

Package Price Qty
1 mg
$500.00
5 mg
$920.00
10 mg
$1,380.00
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Biological Activity

GNE-207 is a novel, potent, and orally bioavailable inhibitor of the bromodomain of CBP. GNE-207 has excellent CBP potency (CBP IC50?=?1?nM, MYC EC50?=?18?nM), and it exhibits a good pharmacokinetic profile.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.58 mL 97.92 mL 195.85 mL
0.5 mM 3.92 mL 19.58 mL 39.17 mL
1 mM 1.96 mL 9.79 mL 19.58 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18844
Actions Inhibitor
M. Wt 510.6
Formula C29H30N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2158266-58-9
Synonyms GNE207, GNE 207
SMILES O=C(NC)C1=NC=C(C2=CC3=C(C=N2)C(C4=NN(C5CCOCC5)C6=C4CN(C(C)=O)CC6)=CC=C3)C=C1

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