GSK951 is a potent and selective inhibitor of Kallikrein-5 (KLK5), demonstrating an IC50 of 250 pM with over 100-fold selectivity against KLK7 and KLK14. This compound is designed for effective epidermal delivery and has been shown to reduce transepidermal water loss while decreasing pro-inflammatory cytokine expression. GSK951 is valuable for research applications in inflammation and immunology, particularly in studies related to Netherton syndrome.
GSK951 is a potent and selective inhibitor of Kallikrein-5 (KLK5), demonstrating an IC50 of 250 pM with over 100-fold selectivity against KLK7 and KLK14. This compound is designed for effective epidermal delivery and has been shown to reduce transepidermal water loss while decreasing pro-inflammatory cytokine expression. GSK951 is valuable for research applications in inflammation and immunology, particularly in studies related to Netherton syndrome.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
