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Biological Activity
GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel; 20-fold less potent CDK inhibitor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.7 mL | 133.51 mL | 267.02 mL |
| 0.5 mM | 5.34 mL | 26.7 mL | 53.4 mL |
| 1 mM | 2.67 mL | 13.35 mL | 26.7 mL |
| 5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
*The above data is based on the productmolecular weight 374.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21966 |
|---|---|
| Actions | Agonist |
| CAS No. | 1402821-41-3 |
| Formula | C18H26N6OS |
| M. Wt | 374.5 |
| Purity | >98% |
| Synonyms | GV58, GV 58 |
| SMILES | CC[[email protected]@H](NC1=NC(NCC2=CC=C(C)S2)=C3N=CN(CCC)C3=N1)CO |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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