HIV-1 inhibitor-57 is a potent HIV-1 inhibitor that targets reverse transcriptase (RT). Demonstrating activity against both wild-type and several prevalent non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 strains, it exhibits effective EC50 values between 0.024 to 0.0010 μM. This compound enhances binding through additional interactions with critical residues in the HIV-1 RT binding site, making it a valuable tool for HIV research and antiviral drug development.
HIV-1 inhibitor-57 is a potent HIV-1 inhibitor that targets reverse transcriptase (RT). Demonstrating activity against both wild-type and several prevalent non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 strains, it exhibits effective EC50 values between 0.024 to 0.0010 μM. This compound enhances binding through additional interactions with critical residues in the HIV-1 RT binding site, making it a valuable tool for HIV research and antiviral drug development.
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