HIV-1 inhibitor-8 is a potent oral non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1. It demonstrates exceptional antiviral activity across various HIV-1 strains, with an EC50 range of 4.44 to 54.5 nM. Additionally, HIV-1 inhibitor-8 has an IC50 of 0.081 µM against wild-type HIV-1 reverse transcriptase, indicating its potential utility in HIV research and therapeutic applications.
HIV-1 inhibitor-8 is a potent oral non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting HIV-1. It demonstrates exceptional antiviral activity across various HIV-1 strains, with an EC50 range of 4.44 to 54.5 nM. Additionally, HIV-1 inhibitor-8 has an IC50 of 0.081 µM against wild-type HIV-1 reverse transcriptase, indicating its potential utility in HIV research and therapeutic applications.
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