HIV-1 protease-IN-1 is a highly potent inhibitor of the HIV-1 protease, exhibiting an IC50 of 90 pM. This compound demonstrates significant antiviral activity, with EC50 values of 89 nM against the B-HIV strain and 13.59 nM against the C-HIV strain ZM246, as well as an impressive EC50 of 8.23 nM against the C-HIV strain Indie. HIV-1 protease-IN-1 serves as a valuable tool for research and development in HIV treatment strategies and antiviral drug discovery.
HIV-1 protease-IN-1 is a highly potent inhibitor of the HIV-1 protease, exhibiting an IC50 of 90 pM. This compound demonstrates significant antiviral activity, with EC50 values of 89 nM against the B-HIV strain and 13.59 nM against the C-HIV strain ZM246, as well as an impressive EC50 of 8.23 nM against the C-HIV strain Indie. HIV-1 protease-IN-1 serves as a valuable tool for research and development in HIV treatment strategies and antiviral drug discovery.
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