HMC-B17 is a selective inhibitor of HPK1, exhibiting an IC50 of 1.39 nM. It enhances the secretion of IL-2 in Jurkat cells, with an EC50 of 11.56 nM, thereby potentiating the efficacy of anti-PD-L1 therapies. This compound is valuable for research into cancer mechanisms and immunotherapy strategies.
HMC-B17 is a selective inhibitor of HPK1, exhibiting an IC50 of 1.39 nM. It enhances the secretion of IL-2 in Jurkat cells, with an EC50 of 11.56 nM, thereby potentiating the efficacy of anti-PD-L1 therapies. This compound is valuable for research into cancer mechanisms and immunotherapy strategies.
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