Fig. 1 · Structure
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HSGN-94
Antimicrobial Agent
HSGN-94 is a potent antimicrobial agent that targets lipoteichoic acid (LTA) biosynthesis. It effectively inhibits drug-resistant Gram-positive bacteria, demonstrating minimum inhibitory concentration (MIC) values between 0.25-2 μg/mL. HSGN-94 also prevents biofilm formation in methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococci. Additionally, it exhibits anti-inflammatory activity by inhibiting pro-inflammatory cytokines and shows in vivo efficacy in a murine model of MRSA wound infection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2570797-85-0 |
| Applications | Antimicrobial Agent |
| Formula | C23H23F3N4O4S |
| Molecular Weight | 508.51 |
| SMILES | O=S(C1=CC=C(C=C1)C(NC2=NN=C(O2)C3=CC=C(C=C3)C(F)(F)F)=O)(N4C[C@@H](C[C@@H](C4)C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.