Fig. 1 · Structure
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Hydroxy-PEG4-CH2COOH
PROTAC Linkers
Hydroxy-PEG4-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (Proteolysis Targeting Chimera) synthesis. This compound facilitates the conjugation of ligands to E3 ubiquitin ligases, promoting the targeted degradation of specific proteins. It is pivotal in the development of novel therapeutic strategies in oncology and other fields of biomedical research, enabling researchers to explore the potential of targeted protein modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 70678-95-4 |
| Applications | PROTAC Linkers |
| Formula | C10H20O7 |
| Molecular Weight | 252.26 |
| SMILES | O=C(O)COCCOCCOCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.