I-XW-053 sodium is an inhibitor of the HIV-1 capsid protein, demonstrating significant antiviral activity against HIV-189BZ167 with an IC50 value of 164.2 μM. This compound effectively disrupts the interaction between the N-terminal domains of the capsid protein, specifically at the NTD-NTD interface, exhibiting micromolar affinity. I-XW-053 is a valuable tool for research aimed at understanding HIV replication and developing therapeutic strategies against HIV infection.
I-XW-053 sodium is an inhibitor of the HIV-1 capsid protein, demonstrating significant antiviral activity against HIV-189BZ167 with an IC50 value of 164.2 μM. This compound effectively disrupts the interaction between the N-terminal domains of the capsid protein, specifically at the NTD-NTD interface, exhibiting micromolar affinity. I-XW-053 is a valuable tool for research aimed at understanding HIV replication and developing therapeutic strategies against HIV infection.
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