IBG3

Name: IBG3
Brand: Adooq Bioscience
SKU: A24392
Rating: 5 (288 reviews)

Catalog No.: A24392

BRD2/BRD4 Degrader

IBG3 is a dual-JQ1-containing BET molecular glue degrader that promotes protein degradation through intramolecular bivalent glues. It acts as a bifunctional degrader of BRD2 and BRD4, with DC50 values of 8.6 pM and 6.7 pM, respectively.

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Grouped product items
Size	Price	Stock
2mg	$162.00	In stock
5mg	$324.00	In stock
10mg	$630.00	In stock
50mg	$1,854.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	IBG3 is a dual-JQ1-containing BET molecular glue degrader that promotes protein degradation through intramolecular bivalent glues. It acts as a bifunctional degrader of BRD2 and BRD4, with DC50 values of 8.6 pM and 6.7 pM, respectively.

Product Information

Catalog Num	A24392
Formula	C54H57N9O5S2
Molecular Weight	976.22
CAS Number	nan
SMILES	O=C(NCC1=CC=C(C2=N[C@@H](CC(OC(C)(C)C)=O)C3=NN=C(C)N3C4=C2C(C)=C(C)S4)C=C1)C5=CC=C(C6=CC=C(C7=N[C@@H](CC(OC(C)(C)C)=O)C8=NN=C(C)N8C9=C7C(C)=C(C)S9)C=C6)C=C5
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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