Ibrutinib-biotin

Catalog No.: A12238

Ibrutinib-biotin

Ibrutinib-biotin Chemical Structure

CAS NO. 1599432-18-4

Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK.

Availability: In stock

Package Price Qty
5 mg
$720.00
10 mg
$1,240.00
50 mg
$3,680.00
100 mg
$7,360.00
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Biological Activity

Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.11 mL 45.56 mL 91.13 mL
0.5 mM 1.82 mL 9.11 mL 18.23 mL
1 mM 0.91 mL 4.56 mL 9.11 mL
5 mM 0.18 mL 0.91 mL 1.82 mL

*The above data is based on the productmolecular weight 1097.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12238
CAS No. 1599432-18-4
Formula C56H80N12O9S
M. Wt 1097.37
Solubility DMSO
Purity >98%
SMILES O=C(CCCC(NCCCOCCOCCOCCCNC(CCCC[[email protected]@H]1SC[[email protected]](N2)[[email protected]@H]1NC2=O)=O)=O)NCCCCN(C)C/C=C/C(N3CCC[[email protected]@H](N4N=C(C5=CC=C(OC6=CC=CC=C6)C=C5)C7=C(N)N=CN=C74)C3)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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