Fig. 1 · Structure
Documents & Downloads
IleRS-IN-1
IleRS Inhibitor
IleRS-IN-1 is a selective inhibitor of isoleucyl-tRNA synthetase (IleRS), exhibiting a Ki,app of 88 nM. This compound effectively disrupts the aminoacylation process, leading to impaired protein synthesis in cells. It serves as a valuable tool for investigating the role of IleRS in various biological processes and holds potential for therapeutic applications in diseases reliant on protein synthesis regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2502167-19-1 |
| Applications | IleRS Inhibitor |
| Formula | C23H35N5O7S |
| Molecular Weight | 525.62 |
| SMILES | O[C@H]([C@@H]1O)[C@@H](CO[C@@H]1CO[S](NC([C@@H](N)[C@@H](C)CC)=O)(=O)=O)CCCN2C=C(C3=CC=CC=C3)N=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.