Imazalil sulfate is a potent fungicide that primarily targets fungal pathogens in agricultural settings. It exhibits strong activation of the mouse pregnane X receptor (mPXR) while showing minimal interaction with the mouse constitutive androstane receptor (mCAR), indicating its specific metabolic effects. Research indicates that Imazalil sulfate can induce developmental abnormalities, disrupt gut microbiota, and impair hepatic metabolism, making it significant for studies on environmental and toxicological impacts of fungicides.
Imazalil sulfate is a potent fungicide that primarily targets fungal pathogens in agricultural settings. It exhibits strong activation of the mouse pregnane X receptor (mPXR) while showing minimal interaction with the mouse constitutive androstane receptor (mCAR), indicating its specific metabolic effects. Research indicates that Imazalil sulfate can induce developmental abnormalities, disrupt gut microbiota, and impair hepatic metabolism, making it significant for studies on environmental and toxicological impacts of fungicides.
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