Fig. 1 · Structure
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IMB-YH-8
PknB Inhibitor
IMB-YH-8 is a selective inhibitor of the serine/threonine protein kinase PknB, demonstrating potent antibacterial activity against Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of 0.25 µg/mL. This compound is valuable for researchers investigating tuberculosis, providing insights into the mechanisms of bacterial resistance and potential therapeutic strategies. Its targeted action on PknB enhances its relevance in studies aimed at developing new antimicrobial agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 17615-10-0 |
| Applications | PknB Inhibitor |
| Formula | C12H12O4 |
| Molecular Weight | 220.22 |
| SMILES | O=C(/C=C/C(C1=CC=C(C=C1)OC)=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.