Fig. 1 · Structure

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Imnopitant dihydrochloride

NK1 Receptor Antagonist

Imnopitant dihydrochloride is a neurokinin NK1 receptor antagonist that effectively inhibits the action of substance P at the NK1 receptor. This compound demonstrates key biological activity in modulating neurogenic inflammation and pain pathways. It is predominantly used in research applications involving pain management, gastrointestinal disorders, and anxiety models, making it a valuable tool for studying the neurokinin system and its therapeutic potential.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 290296-52-5
Applications NK1 Receptor Antagonist
Formula C28H30Cl2F6N4O
Molecular Weight 623.46
SMILES
O=C(C1=CN=C(N2CCN(C)CC2)C=C1C(C=CC=C3)=C3C)N(C)CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4.[H]Cl.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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