Fig. 1 · Structure
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Imnopitant
NK1 Receptor Antagonist
Imnopitant is a potent NK1 receptor antagonist known for its selective inhibition of the neurokinin-1 receptor. This compound demonstrates significant biological activity in modulating pain, anxiety, and depression-related pathways. It is primarily utilized in pharmacological research to explore therapeutic approaches for stress-related disorders and other conditions linked to neurokinin signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 290297-57-3 |
| Applications | NK1 Receptor Antagonist |
| Formula | C28H28F6N4O |
| Molecular Weight | 550.54 |
| SMILES | O=C(C1=CN=C(N2CCN(C)CC2)C=C1C(C=CC=C3)=C3C)N(C)CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.