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Imnopitant

Catalog No.: A62044
NK1 Receptor Antagonist
Imnopitant is a potent NK1 receptor antagonist known for its selective inhibition of the neurokinin-1 receptor. This compound demonstrates significant biological activity in modulating pain, anxiety, and depression-related pathways. It is primarily utilized in pharmacological research to explore therapeutic approaches for stress-related disorders and other conditions linked to neurokinin signaling.
Imnopitant 290297-57-3 NK1 Receptor Antagonist
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionImnopitant is a potent NK1 receptor antagonist known for its selective inhibition of the neurokinin-1 receptor. This compound demonstrates significant biological activity in modulating pain, anxiety, and depression-related pathways. It is primarily utilized in pharmacological research to explore therapeutic approaches for stress-related disorders and other conditions linked to neurokinin signaling.
Product Information
Catalog NumA62044
FormulaC28H28F6N4O
Molecular Weight550.54
CAS Number290297-57-3
SMILESO=C(C1=CN=C(N2CCN(C)CC2)C=C1C(C=CC=C3)=C3C)N(C)CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Neurokinin Receptors