Influenza A virus-IN-17 is a selective inhibitor targeting Influenza A viruses, demonstrating effective inhibition with EC90 values of 3.5 μM for H3N2 and 2.6 μM for H1N1. This compound effectively disrupts the cap-snatching polymerase activity, as indicated by an EC90 of 2.1 μM against U2-PB2 chimeric mRNA. Influenza A virus-IN-17 is suitable for research in antiviral drug development and understanding Influenza A virus mechanisms.
Influenza A virus-IN-17 is a selective inhibitor targeting Influenza A viruses, demonstrating effective inhibition with EC90 values of 3.5 μM for H3N2 and 2.6 μM for H1N1. This compound effectively disrupts the cap-snatching polymerase activity, as indicated by an EC90 of 2.1 μM against U2-PB2 chimeric mRNA. Influenza A virus-IN-17 is suitable for research in antiviral drug development and understanding Influenza A virus mechanisms.
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