Influenza virus-IN-10 is a dual-target anti-influenza agent that inhibits both the polymerase acidic protein (PAC) with a binding affinity of 8.9 μM and the nucleoprotein (NP) with a binding affinity of 52.5 μM. Exhibiting an EC50 of 1.64 μM against the influenza A virus (H1N1, A/WSN/33), this compound demonstrates broad-spectrum antiviral activity against various strains, including influenza B and multiple subtypes of influenza A. It is a valuable tool for research into influenza virus mechanisms and therapeutic interventions.
Influenza virus-IN-10 is a dual-target anti-influenza agent that inhibits both the polymerase acidic protein (PAC) with a binding affinity of 8.9 μM and the nucleoprotein (NP) with a binding affinity of 52.5 μM. Exhibiting an EC50 of 1.64 μM against the influenza A virus (H1N1, A/WSN/33), this compound demonstrates broad-spectrum antiviral activity against various strains, including influenza B and multiple subtypes of influenza A. It is a valuable tool for research into influenza virus mechanisms and therapeutic interventions.
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