Ipatasertib dihydrochloride

Catalog No.: A21734
pan-Akt inhibitor
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Grouped product items
Product Name Price Stock Qty
Ipatasertib dihydrochloride 2mg
$45.00
In stock
Ipatasertib dihydrochloride 5mg
$90.00
In stock
Ipatasertib dihydrochloride 10mg
$175.00
In stock
Ipatasertib dihydrochloride 50mg
$515.00
In stock
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Biological Activity
Discription Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Targets
Target Value
Product Information
Catalog Num A21734
Formula C24H34Cl3N5O2
Molecular Weight 530.92
CAS Number 1396257-94-5
SMILES ClC1=CC=C([C@@H](CNC(C)C)C(N2CCN(C3=C([C@H](C)C[C@H]4O)C4=NC=N3)CC2)=O)C=C1.[H]Cl.[H]Cl
Synonyms GDC-0068 (dihydrochloride), GDC0068, GDC0068; RG-7440 dihydrochloride, RG7440, RG 7440
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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