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IRBP(651-670) human, mouse

Catalog No.: A64889
Uveitis-inducing Epitope
IRBP (651-670) human, mouse is an epitope derived from the conserved region of interphotoreceptor retinoid binding protein (IRBP), functioning primarily as a uveitis-inducing agent. This specific fragment has been shown to elevate levels of pro-inflammatory cytokines, including IL-1β, IL-6, TNFα, IL-17A, and IL-17F, within ocular tissues. Due to its conservation across human, mouse, and bovine species, IRBP (651-670) is valuable in the study of experimental autoimmune uveitis and related inflammatory processes in ocular research.
IRBP(651-670) human, mouse 1977546-93-2 Uveitis-inducing Epitope
Grouped product items
Size Price Stock Qty
1mg
$50.00
In stock
5mg
$130.00
In stock
10mg
$220.00
In stock
25mg
$410.00
In stock
50mg
$615.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIRBP (651-670) human, mouse is an epitope derived from the conserved region of interphotoreceptor retinoid binding protein (IRBP), functioning primarily as a uveitis-inducing agent. This specific fragment has been shown to elevate levels of pro-inflammatory cytokines, including IL-1β, IL-6, TNFα, IL-17A, and IL-17F, within ocular tissues. Due to its conservation across human, mouse, and bovine species, IRBP (651-670) is valuable in the study of experimental autoimmune uveitis and related inflammatory processes in ocular research.
Product Information
Catalog NumA64889
FormulaC91H151N25O32
Molecular Weight2107.32
CAS Number1977546-93-2
SequenceLeu-Ala-Gln-Gly-Ala-Tyr-Arg-Thr-Ala-Val-Asp-Leu-Glu-Ser-Leu-Ala-Ser-Gln-Leu-Thr
Sequence shorteningLAQGAYRTAVDLESLASQLT
SMILES[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CO)=O)C)=O)CC(C)C)=O)CO)=O)CCC(O)=O)=O)CC(C)C)=O)CC(O)=O)=O)C(C)C)=O)C)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)C)=O)CCC(N)=O)=O)=O)C)=O
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Immunology & Inflammation > IL Receptor