IRE1α-IN-2 is a selective inhibitor of IRE1α, demonstrating an IC50 greater than 200 nM for the splicing of XBP1 mRNA. This compound plays a significant role in the study of the unfolded protein response and its implications in cancer research. It is valuable for elucidating the functions of IRE1α in cellular stress pathways and potential therapeutic interventions.
IRE1α-IN-2 is a selective inhibitor of IRE1α, demonstrating an IC50 greater than 200 nM for the splicing of XBP1 mRNA. This compound plays a significant role in the study of the unfolded protein response and its implications in cancer research. It is valuable for elucidating the functions of IRE1α in cellular stress pathways and potential therapeutic interventions.
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