Isobutylamido thiazolyl resorcinol

Catalog No.: A78011
Tyrosinase Inhibitor
Isobutylamido thiazolyl resorcinol is a selective inhibitor of human tyrosinase with an IC50 of 1.1 μM, demonstrating notable efficacy against melanin production. This compound also shows an IC50 of 108 μM against mushroom tyrosinase, highlighting its specificity. Isobutylamido thiazolyl resorcinol effectively mitigates pigmentation induced by UVB exposure and significantly reduces the visibility of hyperpigmentation related to acne. Its applications in dermatological research make it a valuable tool for studying skin pigmentation processes and developing treatments for skin discoloration disorders.
Grouped product items
Size Price Stock Qty
500mg
$20.00
In stock
1g
$30.00
In stock
5g
$80.00
In stock
10g
$130.00
In stock
25g
$260.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIsobutylamido thiazolyl resorcinol is a selective inhibitor of human tyrosinase with an IC50 of 1.1 μM, demonstrating notable efficacy against melanin production. This compound also shows an IC50 of 108 μM against mushroom tyrosinase, highlighting its specificity. Isobutylamido thiazolyl resorcinol effectively mitigates pigmentation induced by UVB exposure and significantly reduces the visibility of hyperpigmentation related to acne. Its applications in dermatological research make it a valuable tool for studying skin pigmentation processes and developing treatments for skin discoloration disorders.
Product Information
Catalog NumA78011
FormulaC13H14N2O3S
Molecular Weight278.33
CAS Number1428450-95-6
SMILESO=C(C(C)C)NC1=NC(C2=C(O)C=C(O)C=C2)=CS1
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