Isochamaejasmin is a biflavonoid that acts as a potent activator of NF-κB. It exhibits significant anti-cancer properties by inducing apoptosis through the mitochondrial pathway and causing DNA damage in AW1 cells. In addition, Isochamaejasmin demonstrates moderate antiplasmodial activity against P. falciparum with an IC50 of 7.3 μM, while maintaining relatively low cytotoxicity (CC50 of 29.0 μM), making it valuable for various biological research applications.
Isochamaejasmin is a biflavonoid that acts as a potent activator of NF-κB. It exhibits significant anti-cancer properties by inducing apoptosis through the mitochondrial pathway and causing DNA damage in AW1 cells. In addition, Isochamaejasmin demonstrates moderate antiplasmodial activity against P. falciparum with an IC50 of 7.3 μM, while maintaining relatively low cytotoxicity (CC50 of 29.0 μM), making it valuable for various biological research applications.
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