Fig. 1 · Structure
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JAK2/STAT3-IN-1
GP130 Inhibitor
JAK2/STAT3-IN-1 is a potent GP130 inhibitor with an IC50 of 3.04 µM. This compound effectively disrupts the JAK2/STAT3 signaling pathway, demonstrating significant anti-tumor activity. It is a valuable tool for research applications focusing on cancer biology and the development of targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2485758-50-5 |
| Applications | GP130 Inhibitor |
| Formula | C34H35BrF3N5O2 |
| Molecular Weight | 682.57 |
| SMILES | O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.