Fig. 1 · Structure
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JB-95
Antimicrobial Agent
JB-95 is a β-hairpin macrocyclic peptide that functions as an antimicrobial agent, exhibiting strong activity against Escherichia coli. It selectively disrupts the outer membrane of E. coli while leaving the inner membrane intact, making it a valuable tool for researching bacterial cell membrane dynamics and antimicrobial mechanisms. Its specificity and potency make JB-95 a promising candidate for studying antimicrobial resistance and developing new therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1873323-60-4 |
| Applications | Antimicrobial Agent |
| Formula | C92H151N35O14 |
| Molecular Weight | 1971.41 |
| SMILES | C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@]4(N(C(=O)[C@@]5(N(C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=6C=7C(NC6)=CC=CC7)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC3=O)[H])[H])CCC5)[H])CCC4)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.