JP-2-249

Name: JP-2-249
Brand: Adooq Bioscience
SKU: A40466
Rating: 5 (288 reviews)

Catalog No.: A40466

SMARCA2 Degrader

JP-2-249 is a selective SMARCA2 degrader that functions as a molecular glue. It has been demonstrated to significantly reduce SMARCA2 protein levels in MV-4-11 cells at concentrations ranging from 1 to 10 μM. This compound is valuable for research applications focused on the modulation of cancer-related pathways involving SMARCA2.

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Biological Activity

Description	JP-2-249 is a selective SMARCA2 degrader that functions as a molecular glue. It has been demonstrated to significantly reduce SMARCA2 protein levels in MV-4-11 cells at concentrations ranging from 1 to 10 μM. This compound is valuable for research applications focused on the modulation of cancer-related pathways involving SMARCA2.

Product Information

Catalog Num	A40466
Formula	C25H25N5O4
Molecular Weight	459.50
CAS Number	3036530-41-0
SMILES	COC1=CC=C(C(/C=C/C(N2CCN(C3=C(N)N=NC(C4=CC=CC=C4O)=C3)CC2)=O)=O)C=C1

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