JTV-519 free base

Catalog No.: A21846

Ca2+-dependent blocker

JTV-519 free base

JTV-519 free base Chemical Structure

CAS NO. 145903-06-6

TV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties.

Availability: In stock

Package Price Qty
5 mg
$405.00
10 mg
$698.00
50 mg
$2,070.00
100 mg
$4,140.00
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Biological Activity

TV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.55 mL 117.76 mL 235.52 mL
0.5 mM 4.71 mL 23.55 mL 47.1 mL
1 mM 2.36 mL 11.78 mL 23.55 mL
5 mM 0.47 mL 2.36 mL 4.71 mL

*The above data is based on the productmolecular weight 424.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21846
Actions Blocker
M. Wt 424.6
Formula C25H32N2O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 145903-06-6
Synonyms K201 free base, K 201, K-201, JTV 519, JTV519
SMILES COC1=CC=C2C(CN(C(CCN3CCC(CC4=CC=CC=C4)CC3)=O)CCS2)=C1

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