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Kiss2 peptide

Catalog No.: A37189
Neuropeptide
Kiss2 peptide is a neuropeptide that acts as a positive regulator of reproduction. It specifically binds to its receptor, Kiss2R (GPR54), in COS-7 cells, activating PKA and PKC signaling pathways via Gas and Gaq proteins. This interaction subsequently enhances cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) activities, making Kiss2 peptide valuable for research in reproductive biology and neuroendocrine signaling.
Kiss2 peptide 1111070-93-9 Neuropeptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKiss2 peptide is a neuropeptide that acts as a positive regulator of reproduction. It specifically binds to its receptor, Kiss2R (GPR54), in COS-7 cells, activating PKA and PKC signaling pathways via Gas and Gaq proteins. This interaction subsequently enhances cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) activities, making Kiss2 peptide valuable for research in reproductive biology and neuroendocrine signaling.
Product Information
Catalog NumA37189
FormulaC63H84N16O12
Molecular Weight1257.44
CAS Number1111070-93-9
SequencePhe-Asn-Phe-Asn-Pro-Phe-Gly-Leu-Arg-Phe-NH2
Sequence shorteningFNFNPFGLRF-NH2
SMILESC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CC2=CC=CC=C2)N)=O)CC(N)=O)=O)=O)CC(N)=O)(=O)N3[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)=O)CCC3
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